ACE Gene mutation

What is an ACE gene?

ACE stands for “angiotensin 1 converting enzyme, this protein regulation the balance of fluids and salts in the body. ACE also stimulates the production of the hormone aldosterone whih is a home that triggers the absorption of salt and water by the kidneys.

ACE causes the activity of the conversion via its enzyme of angiotensin 1 to angiotensin 2. This enzyme is involved in blood pressure regulation and electrolyte balance.

It catalyzes the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This angiotensin-converting enzyme (ACE) also inactivates the vasodilator protein, bradykinin. Accordingly, the encoded enzyme increases blood pressure.

ACE symptoms

Because ACE controls fluid and electrolyte balance, symptoms of an ACE mutation can be very wide-ranging and lead to many serious health problems. Often many people with ACE problems are taking medications to prevent diseases including cardiovascular pathophysiologies (heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease), psoriasis, renal disease, stroke, and Alzheimer’s disease.

The following symptoms can be associated with ACE mutations:

Hypertension / Hypertensive events
Elevated blood pressure
Headaches
Heart disease / Heart attack
Kidney disease
Stroke
Alzheimer’s disease
Human coronaviruses, including SARS-CoV and SARS-CoV-2
Psoriasis
Infertility
Body fluid imbalances
Blood pressure problems including imbalances (low and high)
Inability to calm down your blood pressure from everyday emotional events such as stress

Imbalances of electrolytes such as:

Symptoms of essential electrolyte imbalances

Sodium:

Dizziness
Heat exhaustion
Low blood pressure
Rapid pulse
Mental apathy
Loss of appetite
Muscle cramps
Nausea
Vomiting
Reduced body weight
Headaches

Potassium:

Rapid irregular heartbeat
Muscle weakness
Pins and needles
Irritability
Nausea
Vomiting
Diarrhea
Swollen abdomen
Cellulite
Low blood pressure resulting from an imbalance of potassium: sodium ratio
Confusion
Mental apathy

Magnesium:

Muscle tremors or spasms
Muscle weakness
Insomnia or nervousness
High blood pressure
Irregular heartbeat
Constipation
Fits or convulsions
Hyperactivity
Depression
Confusion
Lack of appetite
Calcium deposits in soft tissue e.g. kidney stones
Low levels of magnesium are also associated with increased rates of heart attack, anxiety, and nervousness

As you can see ACE gene mutations can cause many symptoms and also lead to many diseases. Here is what they may look like, homozygous (double bad copies in red):

Treating ACE gene mutations

If you have ACE gene mutations regardless of them being homozygous or heterozygous, you must treat any active mutations to prevent serious health problems. The good news is that these mutations are treatable. However it is important to do it right using experienced health practitioners. Those who understand the complicated nature of treating ACE gene mutations.

Get a consultation about your ACE mutations from the following link ACE help.