G6PD belongs to the Pentose Phosphate Pathway (PPP). This pathway controls the production of NADPH.
What happens when the PPP is not working like it should because of G6PD deficiency?
- Your red blood cells explode
- Your reduced glutathione has oxidative damage
- CFS/ME due to mitochondrial dysfunction
- Your ferritin increases
- Cannot make PAPs
- Cannot make ATP
- Shut off the citric acid cycle
- The shutdown of Phase I liver detox where CYP450’s reside
- Circadian rhythm is compromised
- EMF sensitivity sets in
- Higher risk for hemolytic anemia
- Higher risk for POTS (10% of people with POTS are G6PDD)
- Redox signaling becomes impaired
- Higher risk for lupus
- Higher risk of being injured by a fluoroquinolone
If you have mutations in G6PD you can get tested click here to find out more.